Superimposed Hi-C: A Solution Proposed for Identifying Single Cell's Chromosomal Interactions

Autor: Zhang, Jia, Xiao, Li, Qi, Peng, Zeng, Yaling, Chen, Xumeng, Liao, Duan-fang, Li, Kai
Rok vydání: 2024
Předmět:
Druh dokumentu: Working Paper
Popis: Hi-C sequencing is widely used for analyzing chromosomal interactions. In this study, we propose "superimposed Hi-C" which features paired EcoP15I sites in a linker to facilitate sticky-end ligation with target DNAs. Superimposed Hi-C overcomes Hi-C's technical limitations, enabling the identification of single cell's chromosomal interactions.
Databáze: arXiv