Automatic Prediction of Amyotrophic Lateral Sclerosis Progression using Longitudinal Speech Transformer

Autor: Wang, Liming, Gong, Yuan, Dawalatabad, Nauman, Vilela, Marco, Placek, Katerina, Tracey, Brian, Gong, Yishu, Premasiri, Alan, Vieira, Fernando, Glass, James
Rok vydání: 2024
Předmět:
Druh dokumentu: Working Paper
Popis: Automatic prediction of amyotrophic lateral sclerosis (ALS) disease progression provides a more efficient and objective alternative than manual approaches. We propose ALS longitudinal speech transformer (ALST), a neural network-based automatic predictor of ALS disease progression from longitudinal speech recordings of ALS patients. By taking advantage of high-quality pretrained speech features and longitudinal information in the recordings, our best model achieves 91.0\% AUC, improving upon the previous best model by 5.6\% relative on the ALS TDI dataset. Careful analysis reveals that ALST is capable of fine-grained and interpretable predictions of ALS progression, especially for distinguishing between rarer and more severe cases. Code is publicly available.
Databáze: arXiv