X-ray2CTPA: Generating 3D CTPA scans from 2D X-ray conditioning

Autor:	Cahan, Noa, Klang, Eyal, Aviram, Galit, Barash, Yiftach, Konen, Eli, Giryes, Raja, Greenspan, Hayit
Rok vydání:	2024
Předmět:	Electrical Engineering and Systems Science - Image and Video Processing Computer Science - Computer Vision and Pattern Recognition
Druh dokumentu:	Working Paper
Popis:	Chest X-rays or chest radiography (CXR), commonly used for medical diagnostics, typically enables limited imaging compared to computed tomography (CT) scans, which offer more detailed and accurate three-dimensional data, particularly contrast-enhanced scans like CT Pulmonary Angiography (CTPA). However, CT scans entail higher costs, greater radiation exposure, and are less accessible than CXRs. In this work we explore cross-modal translation from a 2D low contrast-resolution X-ray input to a 3D high contrast and spatial-resolution CTPA scan. Driven by recent advances in generative AI, we introduce a novel diffusion-based approach to this task. We evaluate the models performance using both quantitative metrics and qualitative feedback from radiologists, ensuring diagnostic relevance of the generated images. Furthermore, we employ the synthesized 3D images in a classification framework and show improved AUC in a PE categorization task, using the initial CXR input. The proposed method is generalizable and capable of performing additional cross-modality translations in medical imaging. It may pave the way for more accessible and cost-effective advanced diagnostic tools. The code for this project is available: https://github.com/NoaCahan/X-ray2CTPA . Comment: preprint, project code: https://github.com/NoaCahan/X-ray2CTPA
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2406.16109 Zobrazit plný text záznamu View this record from Arxiv