Automated tomographic assessment of structural defects of freeze-dried pharmaceuticals
Autor: | Müller, Patric, Sack, Achim, Dümler, Jens, Heckel, Michael, Wenzel, Tim, Siegert, Teresa, Schuldt-Lieb, Sonja, Gieseler, Henning, Pöschel, Thorsten |
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Rok vydání: | 2024 |
Předmět: | |
Druh dokumentu: | Working Paper |
Popis: | The topology and surface characteristics of lyophilisates significantly impact the stability and reconstitutability of freeze-dried pharmaceuticals. Consequently, visual quality control of the product is imperative. However, this procedure is not only time-consuming and labor-intensive but also expensive and prone to errors. In this paper, we present an approach for fully automated, non-destructive inspection of freeze-dried pharmaceuticals, leveraging robotics, computed tomography, and machine learning. Comment: 20 pages, 6 figures |
Databáze: | arXiv |
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