Comment on 'Exact-corrected confidence interval for risk difference in noninferiority binomial trials'

Autor: Andrés, A. Martín, Tejedor, I. Herranz
Rok vydání: 2024
Předmět:
Druh dokumentu: Working Paper
Popis: The article by Hawila & Berg (2023) that is going to be commented presents four relevant problems, apart from other less important ones that are also cited. First, the title is incorrect, since it leads readers to believe that the confidence interval defined is exact when in fact it is asymptotic. Second, contrary to what is assumed by the authors of the article, the statistic that they define is not monotonic in delta. But it is fundamental that this property is verified, as the authors themselves recognize. Third, the inferences provided by the confidence interval proposed may be incoherent, which could lead the scientific community to reach incorrect conclusions in any practical application. For example, for fixed data it might happen that a certain delta value is within the 90%-confidence interval, but outside the 95%-confidence interval. Fourth, the authors do not validate its statistic through a simulation with diverse (and credible) values of the parameters involved. In fact, one of its two examples is for an alpha error of 70%!
Comment: 6 pages
Databáze: arXiv