Quantitative comparison of cell-cell detachment force in different experimental setups

Autor:	Vishen, Amit Singh, Prost, Jacques, Sens, Pierre
Rok vydání:	2023
Předmět:	Physics - Biological Physics Condensed Matter - Soft Condensed Matter Quantitative Biology - Quantitative Methods
Druh dokumentu:	Working Paper
Popis:	We compare three different setups for measuring cell-cell adhesion. We show that the measured strength depends on the type of setup that is used. For identical cells different assays measure different detachment forces. This can be understood from the fact that cell-cell detachment is a global property of the system. We also analyse the role of external force and line tension on contact angle and cell-cell detachment. Comparison with experiment suggests that the current data are essentially dynamical in nature. We dedicate this article to Fyl Pincus who for many of us is an example to be followed not only for outstanding science but also for a marvelous human behavior. Comment: 7 pages, 5 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2312.13918 Zobrazit plný text záznamu View this record from Arxiv