Reducing societal impacts of SARS-CoV-2 interventions through subnational implementation
| Autor: | Dekker, Mark M., Coffeng, Luc E., Pijpers, Frank P., Panja, Debabrata, de Vlas, Sake J. |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | eLife 12, e80819 (2023) |
| Druh dokumentu: | Working Paper |
| DOI: | 10.7554/eLife.80819 |
| Popis: | To curb the initial spread of SARS-CoV-2, many countries relied on nation-wide implementation of non-pharmaceutical intervention measures, resulting in substantial socio-economic impacts. Potentially, subnational implementations might have had less of a societal impact, but comparable epidemiological impact. Here, using the first COVID-19 wave in the Netherlands as a case in point, we address this issue by developing a high-resolution analysis framework that uses a demographically-stratified population and a spatially-explicit, dynamic, individual contact-pattern based epidemiology, calibrated to hospital admissions data and mobility trends extracted from mobile phone signals and Google. We demonstrate how a subnational approach could achieve similar level of epidemiological control in terms of hospital admissions, while some parts of the country could stay open for a longer period. Our framework is exportable to other countries and settings, and may be used to develop policies on subnational approach as a better strategic choice for controlling future epidemics. Comment: 9 pages, 4 figures and Supplementary Information |
| Databáze: | arXiv |
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