Role of signal degradation in directional chemosensing

Autor:	LeFebre, Ryan, Landsittel, Joseph A., Stone, David E., Mugler, Andrew
Rok vydání:	2023
Předmět:	Physics - Biological Physics
Druh dokumentu:	Working Paper
Popis:	Directional chemosensing is ubiquitous in cell biology, but some cells such as mating yeast paradoxically degrade the signal they aim to detect. While the data processing inequality suggests that such signal modification cannot increase the sensory information, we show using a reaction-diffusion model and an exactly solvable discrete-state reduction that it can. We identify a non-Markovian step in the information chain allowing the system to evade the data processing inequality, reflecting the nonlocal nature of diffusion. Our results apply to any sensory system in which degradation couples to diffusion. Experimental data suggest that mating yeast operate in the beneficial regime where degradation improves sensing. Comment: 13 pages, 3 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2310.01648 Zobrazit plný text záznamu View this record from Arxiv