| Autor: |
Gökçe, Aytül, Gürbüz, Burcu, Rendall, Alan D. |
| Rok vydání: |
2023 |
| Předmět: |
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| Druh dokumentu: |
Working Paper |
| Popis: |
The COVID-19 pandemic led to widespread interest in epidemiological models. In this context the role of vaccination in influencing the spreading of the disease is of particular interest. There has also been a lot of debate on the role of non-pharmaceutical interventions such as the disinfection of surfaces. We investigate a mathematical model for the spread of a disease which includes both imperfect vaccination and infection due to virus in the environment. The latter is studied with the help of two phenomenological models for the force of infection. In one of these models we find that backward bifurcations take place so that for some parameter values an endemic steady state exists although the basic reproduction ratio $R_0$ is less than one. We also prove that in that case there can exist more than one endemic steady state. In the other model all generic transcritical bifurcations are forward bifurcations so that these effects cannot occur. Thus we see that the occurrence of backward bifurcations, which can be important for disease control strategies, is dependent on the details of the function describing the force of infection. By means of simulations the predictions of this model are compared with data for COVID-19 from Turkey. A sensitivity analysis is also carried out. |
| Databáze: |
arXiv |
| Externí odkaz: |
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