Involvement of calcium channels Orai3 in the chemoresistance to cisplatin in non-small cell lung cancer (NSCLC)

Autor:	Daoudi, Rédoane
Rok vydání:	2023
Předmět:	Quantitative Biology - Tissues and Organs Quantitative Biology - Subcellular Processes
Druh dokumentu:	Working Paper
Popis:	This is the second part of the previous review. In the previous review we suspected that Orai3 channels were involved in lung cancer and more precisely in several cancers. Here we confirm that calcium dysregulation is important for cancer development. in this paper we show that Orai3 is an upstream activator of AKT and we prove that AKT is involved in chemoresistance in NSCLC. Comment: 24 pages, 6 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2307.10289 Zobrazit plný text záznamu View this record from Arxiv