Shape-tension coupling produces nematic order in an epithelium vertex model

Autor: Rozman, Jan, Sknepnek, Rastko, Yeomans, Julia M.
Rok vydání: 2022
Předmět:
Druh dokumentu: Working Paper
Popis: We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived $+1$ defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning.
Databáze: arXiv