Lung Ultrasound Segmentation and Adaptation between COVID-19 and Community-Acquired Pneumonia
| Autor: | Mason, Harry, Cristoni, Lorenzo, Walden, Andrew, Lazzari, Roberto, Pulimood, Thomas, Grandjean, Louis, Wheeler-Kingshott, Claudia AM Gandini, Hu, Yipeng, Baum, Zachary MC |
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| Rok vydání: | 2021 |
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| Druh dokumentu: | Working Paper |
| Popis: | Lung ultrasound imaging has been shown effective in detecting typical patterns for interstitial pneumonia, as a point-of-care tool for both patients with COVID-19 and other community-acquired pneumonia (CAP). In this work, we focus on the hyperechoic B-line segmentation task. Using deep neural networks, we automatically outline the regions that are indicative of pathology-sensitive artifacts and their associated sonographic patterns. With a real-world data-scarce scenario, we investigate approaches to utilize both COVID-19 and CAP lung ultrasound data to train the networks; comparing fine-tuning and unsupervised domain adaptation. Segmenting either type of lung condition at inference may support a range of clinical applications during evolving epidemic stages, but also demonstrates value in resource-constrained clinical scenarios. Adapting real clinical data acquired from COVID-19 patients to those from CAP patients significantly improved Dice scores from 0.60 to 0.87 (p < 0.001) and from 0.43 to 0.71 (p < 0.001), on independent COVID-19 and CAP test cases, respectively. It is of practical value that the improvement was demonstrated with only a small amount of data in both training and adaptation data sets, a common constraint for deploying machine learning models in clinical practice. Interestingly, we also report that the inverse adaptation, from labelled CAP data to unlabeled COVID-19 data, did not demonstrate an improvement when tested on either condition. Furthermore, we offer a possible explanation that correlates the segmentation performance to label consistency and data domain diversity in this point-of-care lung ultrasound application. Comment: Accepted to MICCAI ASMUS Workshop |
| Databáze: | arXiv |
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