Acoustophoresis in polymer-based microfluidic devices: modeling and experimental validation
| Autor: | Lickert, Fabian, Ohlin, Mathias, Bruus, Henrik, Ohlsson, Pelle |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | J. Acoust. Soc. Am. 149, 4281-4291(2021) |
| Druh dokumentu: | Working Paper |
| DOI: | 10.1121/10.0005113 |
| Popis: | A finite-element model is presented for numerical simulation in three dimensions of acoustophoresis of suspended microparticles in a microchannel embedded in a polymer chip and driven by an attached piezoelectric transducer at MHz frequencies. In accordance with the recently introduced principle of whole-system ultrasound resonances, an optimal resonance mode is identified that is related to an acoustic resonance of the combined transducer-chip-channel system and not to the conventional pressure half-wave resonance of the microchannel. The acoustophoretic action in the microchannel is of comparable quality and strength to conventional silicon-glass or pure glass devices. The numerical predictions are validated by acoustic focusing experiments on 5-um-diameter polystyrene particles suspended inside a microchannel, which was milled into a PMMA-chip. The system was driven anti-symmetrically by a piezoelectric transducer, driven by a 30-V peak-to-peak AC-voltage in the range from 0.5 to 2.5 MHz, leading to acoustic energy densities of 13 J/m^3 and particle focusing times of 6.6 s. Comment: 12 pages, 7 pdf figures, pdf-latex |
| Databáze: | arXiv |
| Externí odkaz: |
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