A Proton Computed Tomography Demonstrator for Stopping Power Measurements

Autor: Ulrich-Pur, Felix, Bergauer, Thomas, Burker, Alexander, Hirtl, Albert, Irmler, Christian, Kaser, Stefanie, Pitters, Florian
Rok vydání: 2021
Předmět:
Druh dokumentu: Working Paper
DOI: 10.1088/1742-6596/2374/1/012180
Popis: Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors from x-ray computed tomography (CT) measurements to RSP introduce uncertainties in the applied dose distribution. Using a proton computed tomography (pCT) system to measure the SP directly could potentially increase the accuracy of treatment planning. A pCT demonstrator, consisting of double-sided silicon strip detectors (DSSD) as tracker and plastic scintillator slabs coupled to silicon photomultipliers (SiPM) as a range telescope, was developed. After a significant hardware upgrade of the range telescope, a 3D tomogram of an aluminium stair phantom was recorded at the MedAustron facility in Wiener Neustadt, Austria. In total, 80 projections with 6.5x10^5 primary events were acquired and used for the reconstruction of the RSP distribution in the phantom. After applying a straight-line approximation for the particle path inside the phantom, the most probable value (MPV) of the RSP distribution could be measured with an accuracy of 0.59%. The RSP resolution inside the phantom was only 9.3% due to a limited amount of projections and measured events per projection.
Comment: Preprint submitted to the open-access Journal of Physics: Conference Series. (TIPP2021 conference proceedings). IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it
Databáze: arXiv