Mesoscale microscopy for micromammals: image analysis tools for understanding the rodent brain

Autor:	Tyson, Adam L, Margrie, Troy W
Rok vydání:	2021
Předmět:	Quantitative Biology - Neurons and Cognition Quantitative Biology - Quantitative Methods
Druh dokumentu:	Working Paper
Popis:	Over the last ten years, developments in whole-brain microscopy now allow for high-resolution imaging of intact brains of small rodents such as mice. These complex images contain a wealth of information, but many neuroscience laboratories do not have all of the computational knowledge and tools needed to process these data. We review recent open source tools for registration of images to atlases, and the segmentation, visualisation and analysis of brain regions and labelled structures such as neurons. Since the field lacks fully integrated analysis pipelines for all types of whole-brain microscopy analysis, we propose a pathway for tool developers to work together to meet this challenge. Comment: 24 pages, 3 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2102.11812 Zobrazit plný text záznamu View this record from Arxiv