Leveraging 3D Information in Unsupervised Brain MRI Segmentation
Autor: | Lambert, Benjamin, Louis, Maxime, Doyle, Senan, Forbes, Florence, Dojat, Michel, Tucholka, Alan |
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Rok vydání: | 2021 |
Předmět: | |
Druh dokumentu: | Working Paper |
Popis: | Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle anatomical variability, Unsupervised Anomaly Detection (UAD) methods are proposed, detecting anomalies as outliers of a healthy model learned using a Variational Autoencoder (VAE). Previous work on UAD adopted a 2D approach, meaning that MRIs are processed as a collection of independent slices. Yet, it does not fully exploit the spatial information contained in MRI. Here, we propose to perform UAD in a 3D fashion and compare 2D and 3D VAEs. As a side contribution, we present a new loss function guarantying a robust training. Learning is performed using a multicentric dataset of healthy brain MRIs, and segmentation performances are estimated on White-Matter Hyperintensities and tumors lesions. Experiments demonstrate the interest of 3D methods which outperform their 2D counterparts. Comment: Accepted for presentation at IEEE International Symposium on Biomedical Imaging 2021 |
Databáze: | arXiv |
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