| Autor: |
Genthon, Arthur, Lacoste, David |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Phys. Rev. Research 3, 023187 (2021) |
| Druh dokumentu: |
Working Paper |
| DOI: |
10.1103/PhysRevResearch.3.023187 |
| Popis: |
We obtain general inequalities constraining the difference between the average of an arbitrary function of a phenotypic trait, which includes the fitness landscape of the trait itself, in the presence or in the absence of natural selection. These inequalities imply bounds on the strength of selection, which can be measured from the statistics of trait values and divisions along lineages. The upper bound is related to recent generalizations of linear response relations in Stochastic Thermodynamics, and shares common features with Fisher's fundamental theorem of natural selection, and with its generalization by Price, although they define different measures of selection. The lower bound follows from recent improvements on Jensen's inequality, and both bounds depend on the variability of the fitness landscape. We illustrate our results using numerical simulations of growing cell colonies and with experimental data of time-lapse microscopy experiments of bacteria cell colonies. |
| Databáze: |
arXiv |
| Externí odkaz: |
|
