Micron-scale SABRE-enhanced NV-NMR Spectroscopy
| Autor: | Arunkumar, Nithya, Bucher, Dominik B., Turner, Matthew J., TomHon, Patrick, Glenn, David, Lehmkuhl, Soren, Lukin, Mikhail D., Park, Hongkun, Rosen, Matthew S., Theis, Thomas, Walsworth, Ronald L. |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | PRX Quantum 2, 010305 (2021) |
| Druh dokumentu: | Working Paper |
| DOI: | 10.1103/PRXQuantum.2.010305 |
| Popis: | Optically-probed nitrogen-vacancy (NV) quantum defects in diamond can detect nuclear magnetic resonance (NMR) signals with high-spectral resolution from micron-scale sample volumes of about 10 picoliters. However, a key challenge for NV-NMR is detecting samples at millimolar concentrations. Here, we demonstrate an improvement in NV-NMR proton concentration sensitivity of about $10^5$ over thermal polarization by hyperpolarizing sample proton spins through signal amplification by reversible exchange (SABRE), enabling micron-scale NMR of small molecule sample concentrations as low as 1 millimolar in picoliter volumes. The SABRE-enhanced NV-NMR technique may enable detection and chemical analysis of low concentration molecules and their dynamics in complex micron-scale systems such as single-cells. Comment: 5 pages, 4 figures |
| Databáze: | arXiv |
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