| Popis: |
A typical power calculation is performed by replacing unknown population-level quantities in the power function with what is observed in external studies. Many authors and practitioners view this as an assumed value of power and offer the Bayesian quantity probability of success or assurance as an alternative. The claim is by averaging over a prior or posterior distribution, probability of success transcends power by capturing the uncertainty around the unknown true treatment effect and any other population-level parameters. We use p-value functions to frame both the probability of success calculation and the typical power calculation as merely producing two different point estimates of power. We demonstrate that Go/No-Go decisions based on either point estimate of power do not adequately quantify and control the risk involved, and instead we argue for Go/No-Go decisions that utilize inference on power for better risk management and decision making. |
