Dark-field signal extraction in propagation-based phase-contrast imaging

Autor: Gureyev, T. E., Paganin, D. M., Arhatari, B., Taba, S. T., Lewis, S., Brennan, P. C., Quiney, H. M.
Rok vydání: 2020
Předmět:
Zdroj: Physics in Medicine & Biology 65 215029 (2020)
Druh dokumentu: Working Paper
DOI: 10.1088/1361-6560/abac9d
Popis: A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real decrement to the imaginary part of the complex refractive index, the proposed method requires a single image for extraction of the dark-field signal in two-dimensional projection imaging. In the case of three-dimensional tomographic imaging, the method needs only one image to be collected at each projection angle. A preliminary example demonstrates that this method can improve the visualization of microcalcifications in propagation-based X-ray breast cancer imaging. It is suggested that the proposed approach may be useful in other forms of biomedical imaging, where it can help one to obtain additional small-angle scattering information without increasing the radiation dose to the sample.
Databáze: arXiv