Optical transport of sub-micron lipid vesicles along an optical nanofibre
| Autor: | Yoshino, Takaaki, Yamaura, Daichi, Komiya, Maki, Sugawara, Masakazu, Mitsumori, Yasuyoshi, Niwano, Michio, Hirano-Iwata, Ayumi, Edamatsu, Keiichi, Sadgrove, Mark |
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| Rok vydání: | 2020 |
| Předmět: | |
| Druh dokumentu: | Working Paper |
| DOI: | 10.1364/OE.411124 |
| Popis: | Enhanced manipulation and analysis of bio-particles using light confined in nano-scale dielectric structures has proceeded apace in the last several years. Small mode volumes, along with the lack of a need for bulky optical elements give advantages in sensitivity and scalability relative to conventional optical manipulation. However, manipulation of lipid vesicles (liposomes) remains difficult, particularly in the sub-micron diameter regime. Here we demonstrate the optical trapping and transport of sub-micron diameter liposomes along an optical nanofiber using the nanofiber mode's evanescent field. We find that nanofiber diameters below a nominal diffraction limit give optimal results. Our results pave the way for integrated optical transport and analysis of liposome-like bio-particles, as well as their coupling to nano-optical resonators. Comment: This version includes supplementary material in the appendix. Second version: revised abstract, introduction, added references, corrected small errors and typos |
| Databáze: | arXiv |
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