Regulation of interferon production as a potential strategy for COVID-19 treatment

Autor:	Deng, Xiaobing, Yu, Xiaoyu, Pei, Jianfeng
Rok vydání:	2020
Předmět:	Quantitative Biology - Molecular Networks Quantitative Biology - Subcellular Processes
Druh dokumentu:	Working Paper
Popis:	Regulating the upstream of the cytokines production could be a promising strategy to the treatment of COVID-19. We suggest to pay more attention to the dysregulated IFN-I production in COVID-19 and to considerate cGAS, ALK and STING as potential therapeutic targets preventing cytokine storm. Approved drugs like suramin and ALK inhibitors are worthy of clinical trials. Comment: 9 pages, 3 figure
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2003.00751 Zobrazit plný text záznamu View this record from Arxiv