Synthesis, Functionalization and Properties of Uniform Europium-doped Sodium Lanthanum Tungstate and Molybdate (NaLa(XO$_4$)$_2$, X= Mo,W) probes for Luminescent and X-ray Computed Tomography Bioimaging

Autor: Laguna, Mariano, Nuñez, Nuria O., Becerro, Ana I., Lozano, Gabriel, Moros, Maria, de la Fuente, Jesús M, Corral, Ariadna, Balcerzyk, Marcin, Ocañaa, Manuel
Rok vydání: 2019
Předmět:
Zdroj: Journal of Colloid and Interface Science, Volume 554, 15 October 2019, Pages 520-530
Druh dokumentu: Working Paper
DOI: 10.1016/j.jcis.2019.07.031
Popis: A one-pot simple procedure for the synthesis of uniform, ellipsoidal Eu3+-doped sodium lanthanum tungstate and molybdate (NaLa(XO4)2, X = W, Mo) nanophosphors, functionalized with carboxylate groups, is described. The method is based on a homogeneous precipitation process at 120 C from appropriate Na+, Ln3+ and tungstate or molybdate precursors dissolved in ethylene glycol/water mixtures containing polyacrylic acid. A comparative study of the luminescent properties of both luminescent materials as a function of the Eu3+ doping level has been performed to find the optimum nanophosphor, whose efficiency as X-ray computed tomography contrast agent is also evaluated and compared with that of a commercial probe. Finally, the cell viability and colloidal stability in physiological pH medium of the optimum samples have also been studied to assess their suitability for biomedical applications.
Databáze: arXiv