A mechanistic model of disjunctive metabolic symbioses in microbes

Autor: Fischer, Matthias M.
Rok vydání: 2019
Předmět:
Druh dokumentu: Working Paper
Popis: Lately, experimental research on microbial symbioses based on nutrient exchange and interdependence has yielded a number of interesting findings, however an in-depth mathematical description of the exact underlying dynamics of such symbiotic associations is still missing. Here, we derive and analyse a mechanistic mathematical model of such a relationship in a continuous chemostat culture based on five coupled differential equations. The influence of the biological traits of the involved organisms on the position and stability of the equilibrium states of the system is examined. We also demonstrate how manipulating the external metabolite concentrations of the system can shift the species interaction on a continuous spectrum ranging from mutualism over commensalism to parasitism.
Comment: 19 pages, 4 figures
Databáze: arXiv