Optimal compressive multiphoton imaging at depth using single-pixel detection

Autor: Wijesinghe, Philip, Escobet-Montalbán, Adrià, Chen, Mingzhou, Munro, Peter R T, Dholakia, Kishan
Rok vydání: 2019
Předmět:
Druh dokumentu: Working Paper
DOI: 10.1364/OL.44.004981
Popis: Compressive sensing can overcome the Nyquist criterion and record images with a fraction of the usual number of measurements required. However, conventional measurement bases are susceptible to diffraction and scattering, prevalent in high-resolution microscopy. Here, we explore the random Morlet basis as an optimal set for compressive multiphoton imaging, based on its ability to minimise the space-frequency uncertainty. We implement this approach for the newly developed method of wide-field multiphoton microscopy with single-pixel detection (TRAFIX), which allows imaging through turbid media without correction. The Morlet basis is well-suited to TRAFIX at depth, and promises a route for rapid acquisition with low photodamage.
Databáze: arXiv