Shear-driven instabilities of membrane tubes and dynamin-induced scission

Autor:	Al-Izzi, Sami C., Sens, Pierre, Turner, Matthew S.
Rok vydání:	2018
Předmět:	Physics - Biological Physics Condensed Matter - Soft Condensed Matter
Zdroj:	Phys. Rev. Lett. 125, 018101 (2020)
Druh dokumentu:	Working Paper
DOI:	10.1103/PhysRevLett.125.018101
Popis:	Motivated by the mechanics of dynamin-mediated membrane tube fission we analyse the stability of fluid membrane tubes subjected to shear flow in azimuthal direction. We find a novel helical instability driven by the membrane shear flow which results in a non-equilibrium steady state for the tube fluctuations. This instability has its onset at shear rates that may be physiologically accessible under the action of dynamin and could also be probed using in-vitro experiments on membrane nanotubes, e.g. using magnetic tweezers. We discuss how such an instability may play a role in the mechanism for dynamin-mediated membrane tube fission. Comment: Main Text: 5 pages, 3 figures + S.I. 14 pages, 6 figures (Accepted Version)
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1810.05862 Zobrazit plný text záznamu View this record from Arxiv