| Autor: |
Kuriata, Aleksander, Gierut, Aleksandra Maria, Oleniecki, Tymoteusz, Ciemny, Maciej Pawel, Kolinski, Andrzej, Kurcinski, Mateusz, Kmiecik, Sebastian |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nucleic Acids Research, gky356, 2018 |
| Druh dokumentu: |
Working Paper |
| DOI: |
10.1093/nar/gky356 |
| Popis: |
Classical simulations of protein flexibility remain computationally expensive, especially for large proteins. A few years ago, we developed a fast method for predicting protein structure fluctuations that uses a single protein model as the input. The method has been made available as the CABS-flex web server and applied in numerous studies of protein structure-function relationships. Here, we present a major update of the CABS-flex web server to version 2.0. The new features include: extension of the method to significantly larger and multimeric proteins, customizable distance restraints and simulation parameters, contact maps and a new, enhanced web server interface. CABS-flex 2.0 is freely available at http://biocomp.chem.uw.edu.pl/CABSflex2 |
| Databáze: |
arXiv |
| Externí odkaz: |
|
