Modeling mammalian gastrulation with embryonic stem cells

Autor:	Siggia, Eric D., Warmflash, Aryeh
Rok vydání:	2017
Předmět:	Quantitative Biology - Tissues and Organs
Druh dokumentu:	Working Paper
Popis:	Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and molecular processes that shape the embryo. Here we review recent developments in using embryonic stem cells to create both two and three-dimensional culture models that shed light on mammalian gastrulation. Comment: 18 pages, 1 figure
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1712.03335 Zobrazit plný text záznamu View this record from Arxiv