Multiple scattering limit in optical microscopy

Autor: Badon, Amaury, Boccara, A. Claude, Lerosey, Geoffroy, Fink, Mathias, Aubry, Alexandre
Rok vydání: 2017
Předmět:
Zdroj: Opt. Exp. 25, 28914-28934, 2017
Druh dokumentu: Working Paper
DOI: 10.1364/OE.25.028914
Popis: Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical aberrations which limit the observation to depths close to the surface. To predict quantitatively the penetration depth in microscopy, we theoretically derive the single-to-multiple scattering ratio in reflection. From this key quantity, the multiple scattering limit is deduced for various microscopic imaging techniques such as confocal microscopy, optical coherence tomography and related methods.
Comment: 18 pages, 7 figures
Databáze: arXiv