Constructing solutions for a kinetic model of angiogenesis in annular domains

Autor: Carpio, Ana, Duro, Gema, Negreanu, Mihaela
Rok vydání: 2016
Předmět:
Zdroj: Applied Mathematical Modelling 45, 303-322, 2017
Druh dokumentu: Working Paper
DOI: 10.1016/j.apm.2016.12.028
Popis: We prove existence and stability of solutions for a model of angiogenesis set in an annular region. Branching, anastomosis and extension of blood vessel tips are described by an integrodifferential kinetic equation of Fokker-Planck type supplemented with nonlocal boundary conditions and coupled to a diffusion problem with Neumann boundary conditions through the force field created by the tumor induced angiogenic factor and the flux of vessel tips. Our technique exploits balance equations, estimates of velocity decay and compactness results for kinetic operators, combined with gradient estimates of heat kernels for Neumann problems in non convex domains.
Comment: to appear in Applied Mathematical Modelling
Databáze: arXiv