Learning a Hybrid Architecture for Sequence Regression and Annotation

Autor: Zhang, Yizhe, Henao, Ricardo, Carin, Lawrence, Zhong, Jianling, Hartemink, Alexander J.
Rok vydání: 2015
Předmět:
Druh dokumentu: Working Paper
Popis: When learning a hidden Markov model (HMM), sequen- tial observations can often be complemented by real-valued summary response variables generated from the path of hid- den states. Such settings arise in numerous domains, includ- ing many applications in biology, like motif discovery and genome annotation. In this paper, we present a flexible frame- work for jointly modeling both latent sequence features and the functional mapping that relates the summary response variables to the hidden state sequence. The algorithm is com- patible with a rich set of mapping functions. Results show that the availability of additional continuous response vari- ables can simultaneously improve the annotation of the se- quential observations and yield good prediction performance in both synthetic data and real-world datasets.
Comment: AAAI 2016
Databáze: arXiv