| Autor: |
Klein, Sarah, Appert-Rolland, Cécile, Santen, Ludger |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
EPL 107 (2014) 18004 |
| Druh dokumentu: |
Working Paper |
| DOI: |
10.1209/0295-5075/107/18004 |
| Popis: |
Inside cells, various cargos are transported by teams of molecular motors. Intriguingly, the motors involved generally have opposite pulling directions, and the resulting cargo dynamics is a biased stochastic motion. It is an open question how the cell can control this bias. Here we develop a model which takes explicitly into account the elastic coupling of the cargo with each motor. We show that bias can be simply controlled or even reversed in a counterintuitive manner via a change in the external force exerted on the cargo or a variation of the ATP binding rate to motors. Furthermore, the superdiffusive behavior found at short time scales indicates the emergence of motor cooperation induced by cargo-mediated coupling. |
| Databáze: |
arXiv |
| Externí odkaz: |
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