VCF2Networks: applying Genotype Networks to Single Nucleotide Variants data

Autor:	Dall'Olio, Giovanni Marco, Vahdati, Ali R., Jaume, Bertranpetit, Andreas, Wagner, Hafid, Laayouni
Rok vydání:	2014
Předmět:	Quantitative Biology - Populations and Evolution
Druh dokumentu:	Working Paper
Popis:	Summary: Genotype networks are a method used in systems biology to study the innovability of a given phenotype, determining whether the phenotype is robust to mutations, and how do the genotypes associated to it are distributed in the genotype space. Here we developed VCF2Networks, a tool to apply this method to population genetics data, and in particular to single Nucleotide Variants data encoded in the Variant Call file Format (VCF). A complete summary of the properties of the genotype network that can be calculated by VCF2Networks is given in the Supplementary Materials 1. Availability and Implementation: The home page of the project is https://bitbucket.org/dalloliogm/vcf2networks . VCF2Networks is also available directly from the Python Package Index (PyPI), under the name vcf2networks. Comment: 5 pages, 1 table, plus supplementary of 7 pages and 5 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1401.2016 Zobrazit plný text záznamu View this record from Arxiv