Controlling light in scattering media noninvasively using the photo-acoustic transmission-matrix

Autor: Chaigne, T., Katz, O., Boccara, A. C., Fink, M., Bossy, E., Gigan, S.
Rok vydání: 2013
Předmět:
Zdroj: Nature Photonics 8, 58 (2014)
Druh dokumentu: Working Paper
DOI: 10.1038/nphoton.2013.307
Popis: Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most wavefront-shaping works to-date exploited direct access to the target or implanted probes, the challenge is to apply it non-invasively inside complex samples. Ultrasonic-tagging techniques have been recently demonstrated but these require a sequential point-by- point acquisition, a major drawback for imaging applications. Here, we introduce a novel approach to non-invasively measure the optical transmission-matrix inside a scattering medium, exploiting the photo-acoustic effect. Our approach allows for the first time to simultaneously discriminate, localize, and selectively focus light on multiple targets inside a scattering sample, as well as to recover and exploit the scattering medium properties. Combining the powerful approach of the transmission-matrix with the advantages of photoacoustic imaging opens the path towards deep-tissue imaging and light-delivery utilizing endogenous optical contrast.
Databáze: arXiv