Dynamics of Charge Transfer in Ordered and Chaotic Nucleotide Sequences
| Autor: | Fialko, N. S., Lakhno, V. D. |
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| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Mathematical biology and bioinformatics, 1, 1-7 (2006) |
| Druh dokumentu: | Working Paper |
| Popis: | Charge transfer is considered in systems composed of a donor, an acceptor and bridge sites of (AT) nucleotide pairs. For a bridge consisting of 180 (AT) pairs, three cases are dealt with: a uniform case, when all the nucleotides in each strand are identical; an ordered case, when nucleotides in each DNA strand are arranged in an orderly fashion; a chaotic case, when (AT) and (TA) pairs are arranged randomly. It is shown that in all the cases a charge transfer from a donor to an acceptor can take place. All other factors being equal, the transfer is the most efficient in the uniform case, the ordered and chaotic cases are less and the least efficient, accordingly. The results obtained are in agreement with experimental data on long-range charge transfer in DNA. Comment: Published in peer-reviewed open access journal. http://www.matbio.org/article.php?id=23&lang=eng |
| Databáze: | arXiv |
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