Effects of Epistasis and Pleiotropy on Fitness Landscapes

Autor:	Østman, Bjørn
Rok vydání:	2013
Předmět:	Quantitative Biology - Populations and Evolution
Druh dokumentu:	Working Paper
Popis:	The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key components of genetic architecture -- affect the structure of the fitness landscape, and how they affect the ability of evolving populations to adapt despite the difficulty of crossing valleys present in rugged landscapes. Populations are seen to make use of epistatic interactions and pleiotropy to attain higher fitness, and are not inhibited by the fact that valleys have to be crossed to reach peaks of higher fitness. Comment: 10 pages, 6 figures. To appear in "Origin of Life and Evolutionary Mechanisms" (P. Pontarotti, ed.). Evolutionary Biology: 16th Meeting 2012, Springer-Verlag
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1304.3738 Zobrazit plný text záznamu View this record from Arxiv