The balance between excitation and inhibition controls the temporal organization of neuronal avalanches

Autor:	Lombardi, F., Herrmann, H. J., Perrone-Capano, C., Plenz, D., de Arcangelis, L.
Rok vydání:	2012
Předmět:	Quantitative Biology - Neurons and Cognition Condensed Matter - Statistical Mechanics
Druh dokumentu:	Working Paper
Popis:	Neuronal avalanches, measured in vitro and in vivo, exhibit a robust critical behaviour. Their temporal organization hides the presence of correlations. Here we present experimental measurements of the waiting time distribution between successive avalanches in the rat cortex in vitro. This exhibits a non-monotonic behaviour, not usually found in other natural processes. Numerical simulations provide evidence that this behaviour is a consequence of the alternation between states of high and low activity, named up and down states, leading to a balance between excitation and inhibition controlled by a single parameter. During these periods both the single neuron state and the network excitability level, keeping memory of past activity, are tuned by homeostatic mechanisms. Comment: 5 pages, 3 figures, to appear on Physical Review Letters
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1204.6176 Zobrazit plný text záznamu View this record from Arxiv