Dominance of extreme statistics in a prototype many-body Brownian ratchet

Autor: Hohlfeld, Evan, Geissler, Phillip L.
Rok vydání: 2012
Předmět:
Zdroj: J. Chem. Phys. 141, 161101 (2014)
Druh dokumentu: Working Paper
DOI: 10.1063/1.4899052
Popis: Many forms of cell motility rely on Brownian ratchet mechanisms that involve multiple stochastic processes. We present a computational and theoretical study of the nonequilibrium statistical dynamics of such a many-body ratchet, in the specific form of a growing polymer gel that pushes a diffusing obstacle. We find that oft-neglected correlations among constituent filaments impact steady-state kinetics and significantly deplete the gel's density within molecular distances of its leading edge. These behaviors are captured quantitatively by a self-consistent theory for extreme fluctuations in filaments' spatial distribution.
Comment: 5 pages with 3 figures + 20 pages of Supplementary Material with 2 figures. Updated to agree with published version; published as a Communication in J. Chem. Phys
Databáze: arXiv