Multi-plectoneme phase of double-stranded DNA under torsion

Autor:	Emanuel, Marc, Lanzani, Giovanni, Schiessel, Helmut
Rok vydání:	2012
Předmět:	Quantitative Biology - Biomolecules Condensed Matter - Soft Condensed Matter
Druh dokumentu:	Working Paper
Popis:	We use the worm-like chain model to study supercoiling of DNA under tension and torque. The model reproduces experimental data for a much broader range of forces, salt concentrations and contour lengths than previous approaches. Our theory shows, for the first time, how the behavior of the system is controlled by a multi-plectoneme phase in a wide range of parameters. This phase does not only affect turn-extension curves but also leads to a non-constant torque in the plectonemic phase. Shortcomings from previous models and inconsistencies between experimental data are resolved in our theory without the need of adjustable parameters. Comment: 4 pages, 6 figures, submitted, 2 typo's corrected, one reference added
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1204.1324 Zobrazit plný text záznamu View this record from Arxiv