Arrays of Nano-Electromechanical Biosensors Functionalized by Microcontact Printing
Autor: | Salomon, Sven, Leichle, Thierry, Dezest, Denis, Seichepine, Florent, Guillon, Samuel, Thibault, Christophe, Vieu, Christophe, Nicu, Liviu |
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Rok vydání: | 2012 |
Předmět: | |
Druh dokumentu: | Working Paper |
DOI: | 10.1088/0957-4484/23/49/495501 |
Popis: | The biofunctionalization of nanoelectromechanical structures is critical for the development of new classes of biosensors displaying improved performances and higher-level of integration. We propose a modified microcontact printing method for the functionalization and passivation of large arrays of nanocantilevers in a single, self-aligned step. Using fluorescence microscopy and resonant frequency measurements, we demonstrate (1) the bioactivity and the anti-fouling property of deposited antibodies and BSA molecules and (2) the preservation of the nanostructures' mechanical integrity. Comment: 20 pages, 5 figures |
Databáze: | arXiv |
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