Undulation Instability of Epithelial Tissues

Autor:	Basan, Markus, Joanny, Jean-Francois, Prost, Jacques, Risler, Thomas
Rok vydání:	2011
Předmět:	Physics - Biological Physics Condensed Matter - Soft Condensed Matter Physics - Fluid Dynamics Physics - Medical Physics Quantitative Biology - Tissues and Organs
Zdroj:	Phys. Rev. Lett. 106, 158101 (2011)
Druh dokumentu:	Working Paper
DOI:	10.1103/PhysRevLett.106.158101
Popis:	Treating the epithelium as an incompressible fluid adjacent to a viscoelastic stroma, we find a novel hydrodynamic instability that leads to the formation of protrusions of the epithelium into the stroma. This instability is a candidate for epithelial fingering observed in vivo. It occurs for sufficiently large viscosity, cell-division rate and thickness of the dividing region in the epithelium. Our work provides physical insight into a potential mechanism by which interfaces between epithelia and stromas undulate, and potentially by which tissue dysplasia leads to cancerous invasion. Comment: 4 pages, 3 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/1105.2032 Zobrazit plný text záznamu View this record from Arxiv