Agent-Based Modeling of Host-Pathogen Systems: The Successes and Challenges

Autor: Bauer, Amy L., Beauchemin, Catherine A. A., Perelson, Alan S.
Rok vydání: 2008
Předmět:
Zdroj: Information Sciences, Volume 179, Issue 10, 29 April 2009, Pages 1379-1389
Druh dokumentu: Working Paper
DOI: 10.1016/j.ins.2008.11.012
Popis: Agent-based models have been employed to describe numerous processes in immunology. Simulations based on these types of models have been used to enhance our understanding of immunology and disease pathology. We review various agent-based models relevant to host-pathogen systems and discuss their contributions to our understanding of biological processes. We then point out some limitations and challenges of agent-based models and encourage efforts towards reproducibility and model validation.
Comment: LaTeX, 12 pages, 1 EPS figure, uses document class REVTeX 4, and packages hyperref, xspace, graphics, amsmath, verbatim, and SIunits
Databáze: arXiv