A functional clustering algorithm for the analysis of dynamic network data
| Autor: | Feldt, S., Waddell, J., Hetrick, V. L., Berke, J. D., Zochowski, M. |
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| Rok vydání: | 2008 |
| Předmět: | |
| Druh dokumentu: | Working Paper |
| DOI: | 10.1103/PhysRevE.79.056104 |
| Popis: | We formulate a novel technique for the detection of functional clusters in discrete event data. The advantage of this algorithm is that no prior knowledge of the number of functional groups is needed, as our procedure progressively combines data traces and derives the optimal clustering cutoff in a simple and intuitive manner through the use of surrogate data sets. In order to demonstrate the power of this algorithm to detect changes in network dynamics and connectivity, we apply it to both simulated neural spike train data and real neural data obtained from the mouse hippocampus during exploration and slow-wave sleep. Using the simulated data, we show that our algorithm performs better than existing methods. In the experimental data, we observe state-dependent clustering patterns consistent with known neurophysiological processes involved in memory consolidation. Comment: 19 pages, 7 figures, significant changes to structure of paper, added methods sections and new measures |
| Databáze: | arXiv |
| Externí odkaz: |
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