Impact of loop statistics on the thermodynamics of RNA folding

Autor:	Einert, Thomas R., Näger, Paul, Orland, Henri, Netz, Roland R.
Rok vydání:	2008
Předmět:	Condensed Matter - Soft Condensed Matter Condensed Matter - Statistical Mechanics Physics - Biological Physics
Zdroj:	Phys. Rev. Lett. 101, 048103 (2008)
Druh dokumentu:	Working Paper
DOI:	10.1103/PhysRevLett.101.048103
Popis:	Loops are abundant in native RNA structures and proliferate close to the unfolding transition. By including a statistical weight ~ l^{-c} for loops of length l in the recursion relation for the partition function, we show that the calculated heat capacity depends sensitively on the presence and value of the exponent c, even of short t-RNA. For homo-RNA we analytically calculate the critical temperature and critical exponents which exhibit a non-universal dependence on c. Comment: 4 pages, 3 figures, including supplementary information
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/0802.3272 Zobrazit plný text záznamu View this record from Arxiv