New method for the study of psychotropic drug effects under simulated clinical conditions

Autor:	Kudryavtseva, N. N., Avgustinovich, D. F., Bondar, N. P., Tenditnik, M. V., Kovalenko, I. L., Koryakina, L. A.
Rok vydání:	2007
Předmět:	Quantitative Biology - Other Quantitative Biology Quantitative Biology - Quantitative Methods
Druh dokumentu:	Working Paper
Popis:	The sensory contact model allows forming different psychopathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, hypersensitivity, cognition disturbances, anhedonia, alcoholism etc.) produced by repeated agonistic interactions in male mice and investigating the therapeutic and preventive properties of any drug as well as its efficiency under simulated clinical conditions. This approach can be useful for a better understanding of the drugs' action in different stages of disease development in individuals. It is suggested that this pharmacological approach may be applied for the screening of different novel psychotropic drugs. Comment: 15 pages, 9 figures, 5 tables
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/0707.3671 Zobrazit plný text záznamu View this record from Arxiv