Immune System -- Tumor Efficiency Rate as a new Oncological Index for Radiotherapy Treatment Optimization

Autor:	Sotolongo-Grau, O., Rodriguez-Perez, D., Santos-Miranda, J. A., Sotolongo-Costa, O., Antoranz, J. C.
Rok vydání:	2007
Předmět:	Quantitative Biology - Populations and Evolution
Druh dokumentu:	Working Paper
Popis:	A dynamical system model for tumor -- immune system interaction together with a method to mimic radiation therapy are proposed. A large population of virtual patients is simulated following an ideal radiation treatment. A characteristic parameter, the Immune System -- Tumor Efficiency Rate (ISTER), is introduced. ISTER dependence of treatment success and other features is studied. Statistical results allow us to give a patient classification scheme. Radiotherapy treatment biological effective dose (BED) is thus optimized based on the patient physical condition, following the ALARA (As Low As Reasonably Achievable) criterion. Comment: 10 pages, 3 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/0706.0418 Zobrazit plný text záznamu View this record from Arxiv