Lipid Peroxidation In Patients With Multipl Myeloma

Autor: BOLAMAN, Zahit, DEMİR, Süleyman, KÖSEOĞLU, Mehmet H., ENLİ, Yaşar, KADIKÖYLÜ, Gürhan, ASLAN, Diler
Rok vydání: 2000
Předmět:
Zdroj: Volume: 1, Issue: 3 13-15
Meandros Medical And Dental Journal
ISSN: 2149-9063
Popis: Aim of study: We investigated the malondialdehyde (MDA) levels as a parameter of lipid peroxidation in patients with multiple myeloma as a preliminary report. Material and method: Fasting venous blood samples were drawn in 12 patients with multiple myeloma and 15 healthy persons. Serum was separated and frozen at -20 C°. All samples were thawed at room temperature and MDA levels were measured by the method in which MDA reacted with thiobarbituric acid and produced a colored complex. This colored complex was read by optic scale at 532 wavelength. Results: MDA levels were 1.51±0.16nmol/ml in patients withmultiple myeloma and 0.97±0.11 nmol/mlinthe control group (P0.05). Conclusion: Plasma MDA levels were found to be higher in multiple myeloma in comparison to control group (p
Databáze: OpenAIRE