BENİGN PATOLOJİ ÖNTANISI İLE HİSTEREKTOMİ YAPILAN OLGULARDA POSTOPERATİF İNSİDENTAL ENDOMETRİAL PRE-/MALİGN PATOLOJİ SAPTANMA ORANI The Rate of Incidental Malignant Pathologies in Patients Who Underwent Hysterectomy Due to Benign Gynecological Conditions
| Autor: | AYDOĞMUŞ, Hüseyin, KOLSUZ, Zafer, ELMALI, Ferhan, TIRAŞ, Halil İbrahim, AYDOĞMUŞ, Serpil |
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| Jazyk: | turečtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Volume: 8, Issue: 4 25-29 Bozok Tıp Dergisi |
| ISSN: | 2146-4006 2148-2438 |
| Popis: | ÖZETAmaç: Benign endikasyonlarla histerektomi yapılması planlanan ve preoperatif ‘endometrial örnekleme/biyopsi yapılan’ ve ‘yapılmayan veya yapılsa dahi yetersiz materyal nedeniyle sonuç alınamayan’ olgularınpostoperatif endometrium histopatoloji sonuçları ile insidental saptanan endometrial patoloji oranlarınınsaptanmasıdır.Gereç ve Yöntemler: Bu kesitsel çalışmaya benign jinekolojik endikasyonlarla histerektomi operasyonu yapılan163 olgu dahil edildi. Bu olgulardan 100’ünde preoperatif endometrial örnekleme/biyopsi yapılmış veendometrial histopatolojik tanı almıştı (Grup 1). 63 olguda ise preoperatif endometrial patolojik incelemeyapılmamış veya sonucu yetersiz materyal olarak rapor edilmişti. (Grup 2). Olguların demografik verileri ilepostoperatif endometrium histopatolojik inceleme sonuçları kaydedildi ve gruplar arasında karşılaştırıldı.Gruplar arası karşılaştırmalarda independent sample T test, Mann-Whitney testi ve Fisher Ki-kare exact testikullanıldı. p0.05). Postoperatif histopatolojik incelemede her iki grupta insidental saptanan endometrial pre-/malignpatoloji oranları benzerdi (Grup 1’de %3’e karşı Grup 2’de %4.8, p= 0.677). Grup 2’de endometrial pre-/malign patoloji saptanan üç olgu da postmenopozal dönemde idi, 2 olguda ise obezite ve diabet tanılarımevcuttu.Sonuç: Postoperatif insidental endometrial patoloji saptanma oranları benzer olarak saptanmış olsa dahibenign jinekolojik patolojilerle histerektomi yapılması planlanan hastalarda endometrial patolojiler açısındanmevcut risk faktörlerinin belirlenmesi ve özellikle riskli olgularda preoperatif dönemde endometrialincelemenin yapılmasını, histopatolojik tanı yetersiz ise gerekirse tekrarlayan biyopsiler veya histeroskopi ileincelenmesi gerektiğini önermekteyiz.Anahtar Sözcu¨kler: Endometrial biyopsi; Endometrial kanser; Histerektomi; Preoperatif; Postoperatif;İnsidental patolojiABSTRACTObjectives: The aim of this study is to compare endometrial histopathological findings of patients havingbeen exposed to hysterectomy due to benign gynecological conditions, who have been through preoperativeendometrial sampling and the ones who have not yet or whom from no results could be achived due toinadequate sample.Materials and methods: In this cross-sectional study, a total of 163 cases who underwent hysterectomyoperation due to benign gynecological indications were evaluated. Group 1 (n=100) patients were appliedendometrial sampling / biopsy and had histopathological diagnosis preoperatively. Group 2 patients(n=63) had no preoperative endometrial pathologic examination or their endometrial biopsy results wereinadequate for diagnosis. The demographic data of the patients and the results of postoperative endometrialhistopathological examination were recorded and compared between the groups. Comparisons betweenthe two groups were made using the independent sample T-test, Mann-Whitney test, and Fisher’s Chisquaretest. The statistical significance level was accepted as p0,05). Onpostoperative final pathologic examination the incidence of incidental diagnosis of premalignant/malignantendometrial pathology were similar between both groups (3% in Group 1 versus 4.8% in Group 2, p=0.677).All of the three patients who were diagnosed premalignant/malignant endometrial pathology in Group 2were postmenopausal and furthermore two of them had diabetes and obesity.Conclusion: Although our results exposed that two groups have similar incidence of incidental diagnosisof endometrial pathologies, we suggest that current risk factors for endometrial pathology should bedetermined before hysterectomy. In high risk group patients if preoperative histopathologic diagnosis isinsufficient, endometrial biopsy should be performed one more times as required or hysteroscopy shouldbe performed.Keywords: Endometrial biopsy; Endometrial cancer; Hysterectomy; Preoperative; Postoperative; Incidental pathology |
| Databáze: | OpenAIRE |
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