EVALUATION OF BPA LEVELS RELEASED FROM DIFFERENT DENTAL RESTORATIVE MATERIALS USING HPLC METHOD

Autor: ASCİ, Ali, DERELİOGLU, Sera Simsek, YİLMAZ, Bilal, GURBUZ, Taskin, SONGUR, Fatma
Rok vydání: 2017
Předmět:
Zdroj: 2.İnternational Congress Of Forensic Toxicology; Volume: Volume 2, Issue: İssue 1 (1) 276-276
The Turkish Journal Of Occupational / Environmental Medicine and Safety
ISSN: 2149-4711
Popis: Bisphenol A(BPA) is a chemical produced in large quantities for use primarily in theproduction of polycarbonate plastics and epoxy resins. BPA is also present indental materials used to treat and prevent caries. There have been concernsraised regarding the safety of bisphenol A in dental sealants and composites.The aim of the study is to measure BPA levels which were released fromcomposite resins after curing with different polymerization conditions. Fourcomposite resins which are commonly used in dental clinics were used in thestudy. The resins were placed into a silicon mold (diameter: 5 mm; thickness: 2mm) on a teflon plate and photopolymerized by LED light source using twodifferent modes [Full-Mod (Mod-1) and Ramping Mod (Mod-2)]. Afterpolymerization, cured composite resin specimens were soaked in 3 ml artificialsaliva and stored at 37 C for 16 days. After 2 h, 24 h, 3 d, 7 d and 15 d, 250µl specimens were taken in order to detect BPA release from dental resins byHPLC-UV detection. The linear ranges were found to be 5-2000 ppb. Theregression equation was y=2.6726x-4.6396 (r =0.9993). Maximum and minimum BPArelease from dental composites detected in Mod 1 were 174.04±9.7 and 9.30±0.16while 10.15±0.3 and 218.0±9.5 in Mod 2, respectively. Release of BPA fromdental restorative materials was ended after 15 days. In conclusion the absenceof a continuous release of BPA from the dental materials is important in theclinical sense. 
Databáze: OpenAIRE