The effect of Tarantula Cubensis extract applied in pre and postoperative period of canine mammary tumours
| Autor: | GÜLTİKEN, Nilgün, VURAL, Mehmet Rıfat |
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| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Issue: 2 13-23 Journal of Istanbul Veterinary Sciences |
| ISSN: | 2602-3490 |
| Popis: | Background:The purpose of the research was to investigate the effects of Tarantulacubensis extract (Theranekron, 1:100 / D2, Richter Pharma, Austria) appliedduring pre and postoperative period on canine mammary tumours. Methods : A total of 30 bitches betweenthe ages of 5-12 were used in the study. The breed distribution of the bitcheswas observed as 21 Terriers, two Pekinese, two St. Bernards, one Setter, oneDanua, one German Shepherd, one Doberman and one Cocker. Group I consisted 20bitches with mammary tumours andsubcutaneus injections of Tarantula cubensis extract were performedpreoperatively for three times at one week intervals with the dosage of 3 mlper 10 kg. Between the days of 7th and 10th following the third injection,complete unilateral mastectomy was performed and injections were repeated atthe 1st and 5th month of postoperative period. Histopathologic results of thisgroup revealed that 10 mammary tumourswere malignant and 10 was benign. Group I was compared to GroupII consisted of 10 bitches with malignant tumourswhich were treated by surgical excision alone. Results: In group I, no change was observed with palpation orinspection after the first Tarantula cubensis extract injection. A week laterthe second injection there was 10% regression in 10 cases. Benign tumours(n=10) were observed to be hard and regressed 50% in the week following the 3rdTarantula cubensis extract injenction performed preoperatively while malignantones showed no regression but became hard. Reoccurence on the intact mammarychain was not observed for a year of postoperative period in Group I. In Group II reoccurence was observed in sixbitches and pulmonary metastasis was determined in two. Conclusion: It was determined that Tarantula cubensis extractapplications in the bitch resulted in regression and hardness of benign mammarytumours while only hardness was detected in malignant mammary tumours.Postoperative injections can be performed in order to prevent the reoccurence. |
| Databáze: | OpenAIRE |
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